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[导管扩张综合征。乳腺疾病患者的前瞻性临床研究]

[The duct ectasia syndrome. A prospective clinical study of patients with breast diseases].

作者信息

Petersen L, Graversen H P, Andersen J A, Dyreborg U, Blichert-Toft M

机构信息

Odense Sygehus, kirurgisk afdeling K.

出版信息

Ugeskr Laeger. 1993 May 17;155(20):1545-9.

PMID:8316986
Abstract

Mammary duct ectasia is a benign condition of the mammary gland histopathologically characterized by inflammatory changes in the collecting ducts. A prospective clinical and histopathological study was done of 316 consecutive patients with surgical mammary diseases. The syndrome of mammary duct ectasia (DES) was found in 42 patients (13%). The mean age was 44 years and 81% of the patients were pre- or menopausal. Forty-eight percent of the patients had a history of previous benign breast lesions and abnormality associated with lactation was also frequently represented in the history. Major symptoms were tumour formation, localised in the subareolar region in more than half of the cases, subareolar abscess and nipple discharge. Minor symptoms were mastalgia, mammary fistula, nipple retraction, general symptoms and enlarged axillary lymph nodes. Treatment for an abscess in DES seems to fail more often if only incision and drainage are performed. Excision of the entire focus and corresponding duct may prove to be better.

摘要

乳腺导管扩张症是一种乳腺的良性疾病,其组织病理学特征为集合管的炎症改变。对316例连续性乳腺外科疾病患者进行了一项前瞻性临床和组织病理学研究。在42例患者(13%)中发现了乳腺导管扩张症(DES)综合征。平均年龄为44岁,81%的患者处于绝经前或绝经状态。48%的患者有既往良性乳腺病变史,病史中也经常出现与泌乳相关的异常情况。主要症状为肿瘤形成,半数以上病例位于乳晕下区域,乳晕下脓肿和乳头溢液。次要症状为乳房疼痛、乳腺瘘、乳头回缩、全身症状和腋窝淋巴结肿大。如果仅进行切开引流,DES脓肿的治疗似乎更容易失败。切除整个病灶及相应导管可能效果更好。

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