da Cunha S, Ferreira E, Ramos I, Martins R, de Freitas L, Borges J L, Côrte-Real R, Mota A, Meliço-Silvestre A, Linhares-Furtado A
Clínica de Doenças Infecciosas, Serviço de Urologia e Transplantação, Hospitais da Universidade de Coimbra.
Acta Med Port. 1993 Mar-Apr;6(3-4):157-63.
Infection caused by Toxoplasma gondii is a frequent event in Portugal. When this occurs in immunocompetent individuals it is rarely a matter of concern; the contrary occurs with immunosuppressed patients or in pregnancy. Transplant patients are treated with immunosuppressive drugs which mainly disturb their mechanisms of cellular immunity, and that opens the way to infections by opportunistic intracellular microorganisms. We recently treated a renal transplant patient who suffered from cerebral toxoplasmosis, and this provided an opportunity for a review of the other 20 patients reported in medical literature to date.
由刚地弓形虫引起的感染在葡萄牙是一种常见事件。当这种情况发生在免疫功能正常的个体中时，很少会引起关注；而在免疫抑制患者或孕期则情况相反。移植患者接受免疫抑制药物治疗，这些药物主要干扰其细胞免疫机制，从而为机会性细胞内微生物感染开辟了道路。我们最近治疗了一名患有脑弓形虫病的肾移植患者，这为回顾迄今为止医学文献中报道的其他20例患者提供了机会。
