一名患有J链病患者浆细胞的超微结构

Ultrastructure of plasma cells in a patient with J chain disease.

作者信息

Sawamura M, Kurabayashi H, Murakami H, Sakura T, Tamura J, Kubota K, Naruse T, Tsuchiya J

机构信息

Third Department of Internal Medicine, Gunma University School of Medicine, Japan.

出版信息

Am J Hematol. 1993 May;43(1):63-5. doi: 10.1002/ajh.2830430116.

DOI:10.1002/ajh.2830430116

PMID:8317467

Abstract

Ultrastructural analysis of plasma cells was performed in a 74-year-old female patient with J chain disease. By electron microscopy, various characteristic findings were observed: lobulated nuclei, multinuclei, single sac loop-like structures, flocculent filament-like substances, nuclear inclusion bodies, cytoplasmic inclusion bodies, and multilamellar bodies. Our prior studies pointed out a poor prognosis in myeloma patients with these findings.

摘要

对一名患有J链病的74岁女性患者的浆细胞进行了超微结构分析。通过电子显微镜观察到了各种特征性表现：分叶核、多核、单囊环样结构、絮状丝状物质、核内包涵体、胞质内包涵体和多层小体。我们之前的研究指出，有这些表现的骨髓瘤患者预后较差。