Doherty C M, Silver B, Binor Z, Molo M W, Radwanska E
Department of Obstetrics and Gynecology, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois.
Am J Obstet Gynecol. 1993 Jun;168(6 Pt 1):1702-7; discussion 1707-9. doi: 10.1016/0002-9378(93)90680-h.
The goal of this study was to determine if ultrasonography of the endometrium could be used to identify in a noninvasive manner patients with luteal phase defects.
Patients underwent midluteal transvaginal ultrasonography with photographing of the endometrial image, an endometrial biopsy, and two serum hormonal profiles. The ultrasonographic images were graded and compared with the histologic results and the serum hormonal profiles.
There was a trend toward a higher grade image being associated with normal histologic studies. There was no significant difference between the mean hormonal profiles in patients with normal and those with abnormal biopsy specimens. There was no significant difference between the hormonal values drawn before and those drawn after the biopsies.
Although the endometrial appearance on ultrasonography appears to reflect secretory transformation, it cannot replace endometrial biopsy for full evaluation of luteal endometrial development. Short-term variability in serum concentrations of midluteal hormones was not demonstrated.
本研究的目的是确定子宫内膜超声检查是否可用于以非侵入性方式识别黄体期缺陷患者。
患者在黄体中期接受经阴道超声检查，拍摄子宫内膜图像、进行子宫内膜活检，并检测两次血清激素水平。对超声图像进行分级，并与组织学结果和血清激素水平进行比较。
图像分级较高有与组织学检查结果正常相关的趋势。活检标本正常和异常的患者，其平均激素水平之间无显著差异。活检前后所测激素值之间无显著差异。
尽管超声检查时子宫内膜的表现似乎反映了分泌期转化，但在全面评估黄体期子宫内膜发育方面，它不能替代子宫内膜活检。未证实黄体中期血清激素浓度存在短期波动。
