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糖尿病患者的产前胎儿监测:何时开始?

Antepartum fetal surveillance in patients with diabetes: when to start?

作者信息

Lagrew D C, Pircon R A, Towers C V, Dorchester W, Freeman R K

机构信息

Saddleback Memorial Women's Hospital, Laguna Hills, CA.

出版信息

Am J Obstet Gynecol. 1993 Jun;168(6 Pt 1):1820-5; discussion 1825-6. doi: 10.1016/0002-9378(93)90696-g.

Abstract

OBJECTIVE

Although antepartum fetal well-being testing is an accepted practice in the management of diabetic patients, there are few data suggesting when to start. Our goal was to examine when testing should be started in the pregnant diabetic woman.

STUDY DESIGN

Antepartum test results and patient histories were prospectively collected on all diabetic pregnancies from January 1981 through December 1991. The data were retrospectively analyzed for when fetal compromise became evident. Fetal compromise was defined as stillbirth, first positive contraction stress test, or intervention because of an abnormal antepartum fetal test result.

RESULTS

Six hundred fourteen patients were enrolled in the study. There were three stillbirths, 45 (7.4%) patients had at least one positive contraction stress test, and 71 (11.6%) patients were delivered because of an abnormal fetal test result. Those with early compromise (< or = 34 weeks' gestation) could not be identified solely by diabetic class. The majority of patients (73%) requiring early intervention because of an abnormal test were class R or F diabetic patients with a growth-retarded fetus or were patients who had a concomitant diagnosis of hypertension.

CONCLUSIONS

Class R or F diabetic patients or diabetic patients with a growth-retarded fetus or a concomitant diagnosis of hypertension may require testing to be started as early as 26 weeks' gestation. Otherwise, testing may be safely delayed until 32 weeks' gestation.

摘要

目的

尽管产前胎儿健康状况检测在糖尿病患者管理中是一种公认的做法,但几乎没有数据表明何时开始检测。我们的目标是研究妊娠糖尿病妇女应何时开始检测。

研究设计

前瞻性收集了1981年1月至1991年12月期间所有糖尿病妊娠的产前检测结果和患者病史。对数据进行回顾性分析,以确定胎儿何时出现明显的健康问题。胎儿健康问题定义为死产、首次阳性宫缩应激试验或因产前胎儿检测结果异常而进行干预。

结果

614名患者纳入研究。有3例死产,45例(7.4%)患者至少有一次阳性宫缩应激试验,71例(11.6%)患者因胎儿检测结果异常而分娩。那些早期出现健康问题(妊娠≤34周)的患者不能仅通过糖尿病类型来识别。大多数因检测异常而需要早期干预的患者(73%)是R级或F级糖尿病患者,伴有胎儿生长受限,或同时诊断为高血压。

结论

R级或F级糖尿病患者、伴有胎儿生长受限或同时诊断为高血压的糖尿病患者可能需要在妊娠26周时就开始检测。否则,检测可安全推迟至妊娠32周。

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