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[艾滋病患者头颈部卡波西肉瘤的临床研究与治疗]

[Clinical studies and treatment of Karposi's sarcoma of the head and neck in AIDS patients].

作者信息

Bujía J, Riederer A, Zietz C, Vogl T, Wilmes E

机构信息

Cátedra de Otorrinolaringología, Ludwig-Maximilians-Universität München.

出版信息

An Otorrinolaringol Ibero Am. 1993;20(3):267-77.

PMID:8317635
Abstract

Kaposi's sarcoma is the major neoplastic disease of HIV-infected patients in the head and neck regions. A clinical study realized at Ludwig-Maximilians University, München, uncover 25 homosexuals with KS out of 135 HIB-positive patients. Six of them showed a KS as initial manifestation of the syndrome. The KS was found principally in the palate (22 cases), oropharynx (12) and skin of the neck (11). Symptoms like swallowing or breathing problems occurred in nodular lesions of the mouth, pharynx or larynx, but no in the maculous type. Local laser and/or systemic (retrovir, interferon, chemotherapy) treatment was performed. CO2 and Nd:YAG laser-therapy showed a regression of the tumors and thus an improvement of quality of life could be achieved.

摘要

卡波西肉瘤是艾滋病毒感染患者头颈部主要的肿瘤性疾病。在慕尼黑路德维希 - 马克西米利安大学进行的一项临床研究发现,135名艾滋病毒阳性患者中有25名同性恋者患有卡波西肉瘤。其中6人表现为卡波西肉瘤是该综合征的初始表现。卡波西肉瘤主要见于腭部(22例)、口咽(12例)和颈部皮肤(11例)。口腔、咽部或喉部的结节性病变会出现吞咽或呼吸问题等症状,但斑疹型则不会。进行了局部激光和/或全身治疗(逆转录病毒、干扰素、化疗)。二氧化碳和钕:钇铝石榴石激光治疗使肿瘤消退,从而提高了生活质量。

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