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前脂肪酶mRNA：组织定位及饮食和肾上腺切除术的影响

Procolipase mRNA: tissue localization and effects of diet and adrenalectomy.

作者信息

Okada S, York D A, Bray G A

机构信息

Louisiana State University, Pennington Biomedical Research Center, Baton Rouge 70808-4124.

出版信息

Biochem J. 1993 Jun 15;292 ( Pt 3)(Pt 3):787-9. doi: 10.1042/bj2920787.

DOI:10.1042/bj2920787
PMID:8318008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1134182/
Abstract

Northern blot analysis has identified procolipase mRNA in rat pancreas, stomach and duodenum. Pancreatic colipase mRNA was increased by high-fat diets. Adrenalectomy increased pancreatic procolipase mRNA, an effect enhanced by high-fat diets. The results suggest that colipase is not unique to the pancreas and that diet and glucocorticoids interact in regulating the transcription of its gene.

摘要

Northern印迹分析已在大鼠胰腺、胃和十二指肠中鉴定出前脂肪酶原mRNA。高脂饮食可使胰腺脂肪酶原mRNA增加。肾上腺切除术可增加胰腺前脂肪酶原mRNA，高脂饮食可增强这种作用。结果表明，脂肪酶并非胰腺所特有，饮食和糖皮质激素在调节其基因转录方面存在相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b58/1134182/74201a27a642/biochemj00109-0172-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b58/1134182/4c02d4b0c9b2/biochemj00109-0172-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b58/1134182/feb6960e5509/biochemj00109-0172-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b58/1134182/74201a27a642/biochemj00109-0172-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b58/1134182/4c02d4b0c9b2/biochemj00109-0172-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b58/1134182/feb6960e5509/biochemj00109-0172-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b58/1134182/74201a27a642/biochemj00109-0172-c.jpg

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本文引用的文献

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Amino acid sequence of horse colipase B.马辅脂酶B的氨基酸序列。
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