前脂肪酶mRNA：组织定位及饮食和肾上腺切除术的影响
Procolipase mRNA: tissue localization and effects of diet and adrenalectomy.
作者信息
Okada S, York D A, Bray G A
机构信息
Louisiana State University, Pennington Biomedical Research Center, Baton Rouge 70808-4124.
出版信息
Biochem J. 1993 Jun 15;292 ( Pt 3)(Pt 3):787-9. doi: 10.1042/bj2920787.
Abstract
Northern blot analysis has identified procolipase mRNA in rat pancreas, stomach and duodenum. Pancreatic colipase mRNA was increased by high-fat diets. Adrenalectomy increased pancreatic procolipase mRNA, an effect enhanced by high-fat diets. The results suggest that colipase is not unique to the pancreas and that diet and glucocorticoids interact in regulating the transcription of its gene.
摘要
Northern印迹分析已在大鼠胰腺、胃和十二指肠中鉴定出前脂肪酶原mRNA。高脂饮食可使胰腺脂肪酶原mRNA增加。肾上腺切除术可增加胰腺前脂肪酶原mRNA，高脂饮食可增强这种作用。结果表明，脂肪酶并非胰腺所特有，饮食和糖皮质激素在调节其基因转录方面存在相互作用。
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