Kozlowski P, Fronk J, Toczko K
Institute of Biochemistry, Warsaw University, Poland.
Biochim Biophys Acta. 1993 Jun 25;1173(3):357-9. doi: 10.1016/0167-4781(93)90139-5.
A ras homologue was identified in the cDNA library from the slime mold Physarum polycephalum. The cDNA codes for a protein of 189 amino acids, showing high homology to ras genes from other organisms, especially to these from Dictyostelium discoideum. Amino acid sequence at the C-terminus of the putative protein suggests that unlike most other ras proteins, it is not palmitoylated and bears a geranylgeranyl rather than farnesyl chain.
在多头绒泡菌的黏菌cDNA文库中鉴定出一种Ras同源物。该cDNA编码一种由189个氨基酸组成的蛋白质,与其他生物体的Ras基因具有高度同源性,尤其是与盘基网柄菌的Ras基因。推测蛋白质C末端的氨基酸序列表明,与大多数其他Ras蛋白不同,它不被棕榈酰化,带有香叶基香叶基链而非法尼基链。