Lund E, Bønaa K H
Institute of Community Medicine, University of Tromsø, Norway.
Cancer Causes Control. 1993 May;4(3):283-7. doi: 10.1007/BF00051323.
International comparisons show that populations having a high consumption of fish experience low incidence of breast cancer. We compared death rates from breast cancer among socioeconomic groups in a prospective study of 533,276 Norwegian women aged 35-54 years who were followed from 1970 through 1985. Compared with the reference group (wives of unskilled workers) the fishermen's wives had a decreased risk of breast cancer with a relative risk (RR) of 0.67 (95% confidence interval [CI] = 0.47-0.94) adjusted for age and the number of children. Among fishermen's wives who were parous, adjustment for age at first birth gave an RR of 0.62 (CI = 0.43-0.91). This study supports the hypothesis that certain aspects of diet, i.e., fish consumption, may be associated with lower breast-cancer mortality.
国际比较显示,鱼类消费量高的人群乳腺癌发病率较低。在一项对533276名年龄在35至54岁的挪威女性进行的前瞻性研究中,我们比较了社会经济群体中乳腺癌的死亡率,这些女性从1970年至1985年一直处于随访中。与参照组(非技术工人的妻子)相比,渔民的妻子患乳腺癌的风险降低,调整年龄和子女数量后的相对风险(RR)为0.67(95%置信区间[CI]=0.47 - 0.94)。在已生育的渔民妻子中,调整首次生育年龄后的RR为0.62(CI = 0.43 - 0.91)。这项研究支持了这样一种假设,即饮食的某些方面,即鱼类消费,可能与较低的乳腺癌死亡率相关。