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超顺磁性颗粒作为经治疗卵巢癌患者磁共振成像的口服造影剂——与普通MRI的比较

Superparamagnetic particles as oral contrast medium in magnetic resonance imaging of patients with treated ovarian cancer--comparison with plain MRI.

作者信息

Prayer L, Stiglbauer R, Kramer J, Wimberger D, Poelzleitner D, Schima W, Kainz C, Koelbl H, Haugen I, Imhof H

机构信息

Department of Radiology, University of Vienna, Austria.

出版信息

Br J Radiol. 1993 May;66(785):415-9. doi: 10.1259/0007-1285-66-785-415.

DOI:10.1259/0007-1285-66-785-415
PMID:8319062
Abstract

In 23 patients with treated ovarian cancer, 24 magnetic resonance (MR) examinations of the abdomen and pelvis were performed before and after administration of an oral superparamagnetic contrast medium. Depiction of bowel loops was judged sufficient in 47% with plain scans and in 85% with enhanced scans. Minor artefacts attributed to the agent were noted in 32% of examinations and were classified as disturbing in 8%. The diagnostic information obtained after contrast enhancement was estimated to be superior to that from plain MRI in 20% of patients. The use of oral contrast medium did not alter the MR diagnosis of "tumour recurrence" or "disease-free" in any patient. Our results suggest that superparamagnetic iron oxide is an effective and reliable approach to negative bowel contrast enhancement, increasing the confidence level when distinguishing intestines from solid structures.

摘要

在23例接受过治疗的卵巢癌患者中,在口服超顺磁性造影剂前后对腹部和盆腔进行了24次磁共振(MR)检查。平扫时47%的检查对肠袢的显示足够,增强扫描时为85%。32%的检查中发现了归因于该造影剂的轻微伪影,其中8%被归类为干扰性伪影。20%的患者中,增强造影后获得的诊断信息估计优于普通MRI。口服造影剂的使用在任何患者中均未改变“肿瘤复发”或“无疾病”的MR诊断。我们的结果表明,超顺磁性氧化铁是一种有效且可靠的阴性肠道造影增强方法,在区分肠道与实性结构时可提高置信度。

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Superparamagnetic particles as oral contrast medium in magnetic resonance imaging of patients with treated ovarian cancer--comparison with plain MRI.超顺磁性颗粒作为经治疗卵巢癌患者磁共振成像的口服造影剂——与普通MRI的比较
Br J Radiol. 1993 May;66(785):415-9. doi: 10.1259/0007-1285-66-785-415.
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