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Severe vascular toxicity associated with cisplatin-based chemotherapy.

作者信息

Içli F, Karaoğuz H, Dinçol D, Demirkazik A, Günel N, Karaoğuz R, Uner A

机构信息

Department of Medicine, Ankara University, School of Medicine, Ibn-i Sina Hospital, Turkey.

出版信息

Cancer. 1993 Jul 15;72(2):587-93. doi: 10.1002/1097-0142(19930715)72:2<587::aid-cncr2820720242>3.0.co;2-v.

Abstract

A 19-year-old man with a germ cell tumor who experienced hypertension, acute myocardial infarction, and cerebrovascular accident (CVA) associated with hypomagnesemia as late complications of cisplatin-based chemotherapy is presented, and previously reported cases in the literature are reviewed. Different physiopathologic mechanisms are hypothesized for early and late vascular complications of cisplatin.

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