Dijkman G E, de Vries J, Lodding A, Arends J
Materia Technica, University of Groningen, The Netherlands.
Caries Res. 1993;27(2):117-23. doi: 10.1159/000261528.
Fluoridated composites are able to reduce or inhibit secondary caries around fillings. The aims of this study were firstly to investigate the amount of F released in vitro from composites with a F content between 0 and 26 vol% as a function of time over a 1-year period. A second aim was to correlate the in vitro data on F release with enamel demineralisation data in situ after a 1-month period. The results show that all fluoridated composites release sizable amounts of F in solution, the total amounts of F released from three composites were proportional to log t over at least 1 year. In one case proportionality of the total amount of F released with t was observed. Possible mechanisms of F release are considered. The results presented also show a linear relation between the log of in vitro F release data and the effects on enamel demineralisation in situ next to the composite. Extrapolation of the data reveals that a F release of about 200-300 micrograms/cm2 over a 1-month period from a fluoridated composite would completely inhibit secondary caries under plaque conditions.
含氟复合树脂能够减少或抑制补牙材料周围的继发龋。本研究的目的,首先是调查含氟量在0至26体积%之间的复合树脂在体外1年期间随时间释放氟的量。第二个目的是将体外氟释放数据与1个月后原位牙釉质脱矿数据相关联。结果表明,所有含氟复合树脂在溶液中都会释放大量氟,三种复合树脂释放的氟总量在至少1年内与log t成正比。在一个案例中,观察到释放的氟总量与t成正比。文中考虑了氟释放的可能机制。给出的结果还表明,体外氟释放数据的对数与复合树脂旁原位牙釉质脱矿的影响之间存在线性关系。数据外推显示,含氟复合树脂在1个月内释放约200 - 300微克/平方厘米的氟,将在菌斑条件下完全抑制继发龋。