Bernstein L H, Shaw-Stiffel T A, Schorow M, Brouillette R
Department of Pathology, Bridgeport Hospital, Connecticut.
Clin Lab Med. 1993 Jun;13(2):491-507.
PEM or the possibility of developing PEM occurs in 30% to 50% of hospitalized patients, the frequency determined by the criteria used in its assessment and the case mix of patients in the hospital population. This condition exists independently of other medical conditions and results from preadmission or postadmission failure to meet nutrient requirements with associated loss of body weight and function, as well as impaired immunity. PEM also frequently arises in patients with a chronic condition and decreased functional reserve when a superimposed acute metabolic stress leads to accelerated nutrient depletion. Whether preexisting or not, PEM increases morbidity and mortality along with LOS and may be associated with complications such as pneumonia, sepsis, operative site infection, delayed wound healing, or decubitus ulcers. The cost of these complications and an extended LOS is a significant financial burden and a controllable medical liability for hospitals. Other costs include identifying patients at risk of PEM, providing nutrition support, not to mention treating any of its complications (mechanical, metabolic, and so forth). A proper analysis of the financial implications of late or untreated PEM versus nutrition support must therefore take into account not only the costs of complications or extended LOS due to the delay or failure to provide nutrition support but also the costs associated with this intervention itself. In this review, we described a model for examining the financial implications of malnutrition and nutritional therapy.
30%至50%的住院患者会出现蛋白质-能量营养不良(PEM)或有发生PEM的可能性,其发生率取决于评估所用的标准以及医院患者群体的病例组合情况。这种情况独立于其他疾病存在,是由于入院前或入院后未能满足营养需求,伴有体重和功能丧失以及免疫力受损所致。当叠加的急性代谢应激导致营养加速消耗时,PEM也常出现在患有慢性疾病且功能储备下降的患者中。无论是否先前就有,PEM都会增加发病率、死亡率以及住院时间(LOS),并且可能与诸如肺炎、败血症、手术部位感染、伤口愈合延迟或压疮等并发症相关。这些并发症的成本以及延长的住院时间对医院来说是巨大的经济负担和可控的医疗责任。其他成本包括识别有PEM风险的患者、提供营养支持,更不用说治疗其任何并发症(机械性、代谢性等等)。因此,对PEM延迟治疗或未治疗与营养支持的财务影响进行恰当分析时,不仅必须考虑因延迟或未能提供营养支持导致的并发症成本或住院时间延长,还必须考虑与这种干预本身相关的成本。在本综述中,我们描述了一个用于研究营养不良和营养治疗财务影响的模型。