Sikorski J M, Pardy B J, Dudley H A
Br J Surg. 1977 Jan;64(1):11-4. doi: 10.1002/bjs.1800640104.
Injection 125I-glyceryl trioleate (0-5 mg/kg) into the right atrium of anaesthetized greyhounds caused the following changes: sequestration of far in the right side of the heart; 95 per cent removal by the lungs in a single passage through the pulmonary circulation; subsequent release of fat into the systemic circulation; rapid overall turnover of fat trapped in the lungs and slow removal of recirculating fat by other tissues. We believe that if there is release of unemulsified fat into the circulation in traumatic fat embolism these findings are of significance in interpreting the subsequent pulmonary events.
将125I-甘油三油酸酯(0 - 5毫克/千克)注入麻醉的灵缇犬右心房会引起以下变化:大量物质滞留于心脏右侧;单次通过肺循环时,肺部清除率达95%;随后脂肪释放进入体循环;滞留在肺部的脂肪整体周转迅速,而其他组织对再循环脂肪的清除缓慢。我们认为,在创伤性脂肪栓塞中若有未乳化脂肪释放入循环,这些发现对于解释随后的肺部事件具有重要意义。