Groome L J, Bentz L S, Singh K P, Mooney D M
Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock.
Early Hum Dev. 1993 Apr;33(1):21-7. doi: 10.1016/0378-3782(93)90170-y.
We examined 96 normal human fetuses between 37 and 41 weeks of gestation to determine the relationship between the duration of the active state following a single vibroacoustic stimulus (VAS) and the time spent in prestimulus state 1F, i.e. quiet sleep (QS). All fetuses were observed to enter state 1F prior to testing. After remaining in this state for 3 min, each fetus was randomized into one of three groups: no stimulation (Group I, N = 32); a single 1-s VAS delivered after 3-5 min of QS (Group II, N = 33); and a single 1-s VAS delivered after 18-20 min of QS (Group III, N = 31). Fetuses in Groups I, II, and III were otherwise behaviourally indistinguishable. Heart rate and eye and body movements were monitored until the fetus either returned to state 1F and remained in that state for 3 min or did not return to state 1F within 60 min. Of the 64 fetuses who were stimulated, 62 responded, indicating that there was no effect of prestimulus state duration on the sensitivity to VAS. Fetuses stimulated after 18-20 min of QS behaved similarly to fetuses who entered an active period spontaneously.(ABSTRACT TRUNCATED AT 250 WORDS)
我们检查了96例妊娠37至41周的正常人类胎儿，以确定单次声振刺激（VAS）后活跃状态的持续时间与刺激前1F状态（即安静睡眠，QS）所花费时间之间的关系。所有胎儿在测试前均被观察到进入1F状态。在该状态下保持3分钟后，将每个胎儿随机分为三组之一：无刺激（I组，N = 32）；在QS 3 - 5分钟后给予单次1秒的VAS（II组，N = 33）；在QS 18 - 20分钟后给予单次1秒的VAS（III组，N = 31）。I、II和III组的胎儿在行为上没有其他差异。监测心率、眼睛和身体运动，直到胎儿要么回到1F状态并在该状态下保持3分钟，要么在60分钟内未回到1F状态。在64例接受刺激的胎儿中，62例有反应，这表明刺激前状态持续时间对VAS敏感性没有影响。在QS 18 - 20分钟后受到刺激的胎儿的行为与自发进入活跃期的胎儿相似。（摘要截断于250字）
