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高度近视的生物力学考量:第三部分——高度近视的治疗

Biomechanical considerations in high myopia: Part III--Therapy for high myopia.

作者信息

Bell G R

出版信息

J Am Optom Assoc. 1993 May;64(5):346-51.

PMID:8320418
Abstract

Clinical procedures for the treatment of high myopia are updated in this third part of a report on high myopia. After a discussion of testing techniques and refractive approaches for high myopia, an examination of therapeutic drug experiences shows their relative merits. The author believes that more investigation of beta blocker and epinephrine topical solutions is needed pertaining to the treatment of high myopia. Theoretically, such agents could improve deficient arterial perfusion of the highly myopic eye, and could be helpful in retarding scleral creep. Lifestyle recommendations include patient advice on accommodative reduction and proper exercise techniques. Low impact aerobics may have merit for highly myopic patients since the improved cardiovascular efficiency they can provide may improve the deficient arterial perfusion of their retinas. A summary of the three-part report on high myopia concludes the article. The physiological patterns of high myopia dovetail into the biomechanical considerations showing that a scleral pathogenesis hypothesis of myopic development is a viable working theory. The author's clinical procedures reflect the influence of that theory. If research were redirected from deprivation studies to investigating biomechanical considerations and pharmacological approaches to high myopia, the author contends that dramatically improved treatment regimens could result.

摘要

这份关于高度近视报告的第三部分更新了高度近视的临床治疗方法。在讨论了高度近视的检测技术和屈光方法之后,对治疗药物经验的研究显示了它们的相对优点。作者认为,关于β受体阻滞剂和肾上腺素局部溶液在高度近视治疗方面还需要更多的研究。从理论上讲,这类药物可以改善高度近视眼动脉灌注不足的情况,并且有助于延缓巩膜延伸。生活方式建议包括向患者提供关于减少调节和正确运动技巧的建议。低强度有氧运动可能对高度近视患者有益,因为其能提高心血管效率,进而改善视网膜动脉灌注不足的情况。本文以关于高度近视的这份三部分报告的总结作为结尾。高度近视的生理模式与生物力学因素相契合,表明近视发展的巩膜发病机制假说是一个可行的工作理论。作者的临床治疗方法体现了该理论的影响。作者认为,如果研究方向从剥夺研究转向对高度近视的生物力学因素和药理学方法的研究,将会产生显著改进的治疗方案。

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