Féry-Lemonnier E, Roux C, Hazebroucq V, Legmann P, Viens-Bitker C
Comité d'Evaluation et de Diffusion des Innovations Technologiques (CEDIT), Hôpitaux de Paris.
J Radiol. 1993 May;74(5):305-10.
The current interest in bone mineral density measurements is related to the frequency, the morbidity and the cost of osteoporosis, which is considered to be a public health problem in developed countries. The main risk factor of osteoporotic fractures is the reduction of bone mineral density. This risk factor can be prevented by hormonal therapy in post-menopausal women. So it is of interest to develop the bone mineral density measurement methods, in osteoporotic bone areas or the entire skeleton (absorptiometry). But the interpretation of the result in term of individual fracture risk, the choice of the bone site to be examined, and the indication of the measurement are still being discussed. A new method of bone status evaluation is currently available: the broad band ultrasonic attenuation, which measures the attenuation of ultrasounds through the calcaneus bone. The device is portable, inexpensive and radiation free, and may give quantitative and qualitative assessment of bone. However, the normal values, the relation with the absorptiometry results and the contribution of this method in fracture risk evaluation are currently studied. Osteoporosis risk evaluation is an important point of health management in post-menopausal women and elderly people. Large prospective studies with the different methods are in progress.
目前对骨密度测量的关注与骨质疏松症的发病率、发病情况及成本有关,在发达国家,骨质疏松症被视为一个公共卫生问题。骨质疏松性骨折的主要风险因素是骨密度降低。绝经后女性可通过激素疗法预防这一风险因素。因此,开发用于骨质疏松骨区域或整个骨骼的骨密度测量方法(吸收测定法)具有重要意义。但关于如何根据个体骨折风险解读测量结果、选择检测的骨部位以及测量的指征仍在讨论中。目前有一种新的骨状态评估方法:宽带超声衰减法,该方法通过跟骨测量超声的衰减。该设备便于携带、价格低廉且无辐射,可对骨骼进行定量和定性评估。然而,目前正在研究其正常值、与吸收测定法结果的关系以及该方法在骨折风险评估中的作用。骨质疏松症风险评估是绝经后女性和老年人健康管理的重要内容。目前正在开展使用不同方法的大型前瞻性研究。