Koo J, Jones A B, Turner F W
Can J Surg. 1977 Jan;20(1):41-4.
The clinical features of spontaneous perforation of the bile ducts in infancy differ sufficiently from those of other causes of neonatal jaundice to allow early preoperative diagnosis as demonstrated by a report of this condition in a 6-week-old infant. Despite its rarity, the clinician should be aware of this entity because early recognition and surgery will ensure cure in almost all cases. The cause of spontaneous perforation of the bile ducts is unknown. Trauma, congenital weakness and abnormal bile are considered as possible etiologic factors.
婴儿期胆管自发性穿孔的临床特征与新生儿黄疸的其他病因有足够的差异,以至于可以进行早期术前诊断,一名6周龄婴儿的这种病症报告就证明了这一点。尽管此病罕见,但临床医生应了解这一病症,因为早期识别并进行手术几乎可确保治愈所有病例。胆管自发性穿孔的病因尚不清楚。创伤、先天性薄弱和胆汁异常被认为是可能的病因。