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防腐剂对特布他林雾化液治疗变应性哮喘疗效的影响。

Effect of preservative on the efficacy of terbutaline nebuliser solution in atopic asthma.

作者信息

Lai C K, Chan C H

机构信息

Department of Medicine, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT.

出版信息

Thorax. 1993 May;48(5):566-8. doi: 10.1136/thx.48.5.566.

Abstract

The efficacy of bronchodilator nebuliser solutions may be influenced by the presence of preservatives. In a double blind, randomised, crossover study the effect of preservatives in determining the airway responses to 5 mg of terbutaline was studied in a group of 21 atopic asthmatic patients. The presence of preservatives affected neither the bronchodilator action of terbutaline nor its protection against bronchoconstriction induced by histamine.

摘要

支气管扩张剂雾化溶液的疗效可能会受到防腐剂的影响。在一项双盲、随机、交叉研究中,对21名特应性哮喘患者组成的小组进行研究,以探讨防腐剂在确定气道对5毫克特布他林反应中的作用。防腐剂的存在既不影响特布他林的支气管扩张作用,也不影响其对组胺诱导的支气管收缩的防护作用。

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Adverse reactions to the non-drug constituents of nebuliser solutions.雾化器溶液中非药物成分的不良反应。
Br J Clin Pharmacol. 1988 Mar;25(3):283-7. doi: 10.1111/j.1365-2125.1988.tb03305.x.
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Am Rev Respir Dis. 1990 Jun;141(6):1423-7. doi: 10.1164/ajrccm/141.6.1423.

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