Haram K, Reigstad H, Markestad T
Kvinneklinikken, Haukeland sykehus, Bergen.
Tidsskr Nor Laegeforen. 1993 May 30;113(14):1698-700.
This article reviews the embryology, pathophysiology, clinical aspects and prophylactic treatment of respiratory distress syndrome (RDS). Prenatal prophylaxis with corticosteroids is indicated for gestational ages between 24 and 32 weeks, even if the effect of prophylaxis is uncertain before the 28th week. Prophylactic treatment is less important between the 32nd and 34th gestational week. Hypertension is not considered a contraindication, but premature rupture of the membranes is a relative contraindication. Corticosteroid treatment may be given, however, in combination with antibiotic prophylaxis.
本文综述了呼吸窘迫综合征(RDS)的胚胎学、病理生理学、临床情况及预防性治疗。对于孕24至32周的孕妇,推荐进行产前糖皮质激素预防,即便在孕28周之前预防效果尚不确定。在孕32至34周之间,预防性治疗的重要性较低。高血压不被视为禁忌证,但胎膜早破是相对禁忌证。不过,糖皮质激素治疗可与抗生素预防联合使用。