Djupesland P, Sauer T, Freng A
Tidsskr Nor Laegeforen. 1993 Jun 20;113(16):1985-7.
In a series of fine needle aspirations performed in 541 patients with visible and/or palpable lesions in the head and neck, histological results were available in 205 the of cases. The cytological and histological diagnoses were compared. In three of the 205 cases the smears were inadequate for diagnosis. Discrepancies were noted in 18 cases (8.7%), and ten false negatives (specificity 91.2) and eight false positives (sensitivity 92.5). The main diagnostic problem was to differentiate between malignant lymphoma and benign lymphadenopathy. Biopsy is therefore recommended when malignant lymphoma is suspected. In this series both the aspirations and the subsequent evaluation of the smears were carried out by a cytopathologist. We conclude that this model increases the accuracy and reliability of fine needle aspiration in head and neck tumours by reducing the number of non-representative smears.
在对541例头颈部有可见和/或可触及病变的患者进行的一系列细针穿刺抽吸中，205例病例有组织学结果。对细胞学和组织学诊断进行了比较。205例病例中有3例涂片不足以用于诊断。发现18例（8.7%）存在差异，10例假阴性（特异性91.2）和8例假阳性（敏感性92.5）。主要诊断问题是区分恶性淋巴瘤和良性淋巴结病。因此，怀疑为恶性淋巴瘤时建议进行活检。在本系列中，穿刺抽吸及随后的涂片评估均由细胞病理学家进行。我们得出结论，该模式通过减少无代表性涂片的数量提高了头颈部肿瘤细针穿刺抽吸的准确性和可靠性。
