Jousela I
Department of Anaesthesia, Helsinki University Central Hospital, Finland.
Acta Anaesthesiol Scand. 1993 May;37(4):381-5. doi: 10.1111/j.1399-6576.1993.tb03733.x.
Various ways of delivering continuous positive airway pressure (CPAP) have been extensively studied, with little attention, however, being paid to the effects of an intubation tube compared with breathing through a face mask, with or without CPAP. Pulmonary and cardiovascular variables were measured while 12 patients recovering from coronary artery bypass grafting were spontaneously breathing at ambient airway pressure, then at 7.4 mmHg (1 kPa) CPAP, and again at ambient pressure just before extubation. The same stages were repeated immediately after extubation, with patients breathing through a tight-fitting face mask. Arterial oxygen tension (Pao2, mean +/- s.d.) was better when the patients were breathing at ambient pressure through a face mask (11.7 +/- 2.8 kPa) than when they were intubated (10.6 +/- 2.4 kPa, P < 0.05). Compared with ambient pressure, CPAP (7.4 mmHg) (1 kPa) increased Pao2 in both modes (13.4 +/- 3.5 kPa with mask, and 12.6 +/- 3.5 kPa when intubated, n.s.). The best arterial oxygen saturation was measured during CPAP with a face mask (96 +/- 1%). Cardiac output remained unchanged in all the breathing modes. After coronary artery bypass grafting, spontaneous breathing with a face mask resulted in better Pao2 than breathing through an endotracheal tube, both with and without 7.4 mmHg (1 kPa) CPAP. This study indicates that unnecessary delay in extubation should be avoided.
持续气道正压通气(CPAP)的多种输送方式已得到广泛研究,然而,与使用或不使用CPAP通过面罩呼吸相比,气管插管的影响却很少受到关注。在12例冠状动脉搭桥术后恢复的患者自主呼吸时,分别在环境气道压力、7.4 mmHg(1 kPa)CPAP以及拔管前再次处于环境压力下测量其肺和心血管变量。拔管后立即重复相同阶段,患者通过紧密贴合的面罩呼吸。患者通过面罩在环境压力下呼吸时的动脉血氧分压(Pao2,均值±标准差)(11.7±2.8 kPa)优于气管插管时(10.6±2.4 kPa,P<0.05)。与环境压力相比,CPAP(7.4 mmHg)(1 kPa)在两种模式下均提高了Pao2(面罩时为13.4±3.5 kPa,气管插管时为12.6±3.5 kPa,无显著差异)。使用面罩进行CPAP时测得的动脉血氧饱和度最佳(96±1%)。所有呼吸模式下的心输出量均保持不变。冠状动脉搭桥术后,无论有无7.4 mmHg(1 kPa)CPAP,通过面罩自主呼吸时的Pao2均优于通过气管内导管呼吸时。本研究表明应避免不必要的拔管延迟。