Rothman A, Tong A D
Department of Pediatrics, University of California, San Diego 92103.
Am Heart J. 1993 Jul;126(1):206-13. doi: 10.1016/s0002-8703(07)80030-5.
Transcatheter Gianturco coil embolization of 26 superfluous but hemodynamically significant vascular connections was attempted in 19 patients with congenital heart disease. There were 18 aortopulmonary collaterals, two vessels involved in pulmonary sequestration, two surgical aortopulmonary shunts (one inadvertently connected from the left subclavian artery to a left upper pulmonary vein), two cases of patent ductus arteriosus, one regurgitant left ventricular-to-descending aorta conduit, and a left superior vena cava-to-left atrium post Fontan procedure. The mean ratio of coil to vessel diameter was 1.6 +/- 0.7, and a mean of 1.5 +/- 1.1 coils were used per vessel. Occlusion was achieved in 24 of 26 attempts (92%), being complete in 21 (81%) and near complete (> 80% decrease in flow) in three (12%). Two attempts failed; a tortuous aortopulmonary collateral was engaged by the delivery catheter but the coil could not be advanced past an acute angle, and another aortopulmonary collateral had a narrow origin and enlarged distally, resulting in coil migration to a distal pulmonary artery branch. One patient had a transient decrease in leg pulses that resolved spontaneously. Fever occurred in four patients (21%) within 12 hours of coil placement, and resolved in all without sequelae or complications. A variety of undesirable vascular connections in patients with congenital heart disease can be safely and effectively treated by percutaneous coil embolization.
对19例先天性心脏病患者尝试经导管用Gianturco弹簧圈栓塞26处多余但具有血流动力学意义的血管连接。其中有18处主肺动脉侧支、2处肺隔离症相关血管、2处外科主肺动脉分流(1处为无意中从左锁骨下动脉连接至左上肺静脉)、2例动脉导管未闭、1例左心室至降主动脉导管反流以及1例Fontan手术后左上腔静脉至左心房连接。弹簧圈与血管直径的平均比例为1.6±0.7,每处血管平均使用1.5±1.1个弹簧圈。26次尝试中有24次(92%)实现闭塞,其中21次(81%)完全闭塞,3次(12%)接近完全闭塞(血流减少>80%)。2次尝试失败;1次为输送导管进入迂曲的主肺动脉侧支,但弹簧圈无法越过锐角推进;另1次为1处主肺动脉侧支起始部狭窄而远端增粗,导致弹簧圈迁移至远端肺动脉分支。1例患者腿部脉搏短暂减弱,随后自行缓解。4例患者(21%)在放置弹簧圈后12小时内出现发热,均无后遗症或并发症而痊愈。经皮弹簧圈栓塞可安全有效地治疗先天性心脏病患者多种不良血管连接。