Hayoz D, Tardy Y, Rutschmann B, Mignot J P, Achakri H, Feihl F, Meister J J, Waeber B, Brunner H R
Division d'Hypertension, Centre de Recherche Cardiovasculaire, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Am J Physiol. 1993 Jun;264(6 Pt 2):H2080-4. doi: 10.1152/ajpheart.1993.264.6.H2080.
In this study we investigated whether there exists a periodic contractile activity of the radial artery, and we evaluated the impact of such an oscillatory behavior on the mechanical properties of this medium-sized muscular vessel. The internal diameter of the right radial artery was measured noninvasively in six healthy male volunteers aged 18-42 yr using a high-precision ultrasonic echo-tracking device. Blood pressure was simultaneously recorded on the same side at the middle finger by photoplethysmography. The electrical activity of the heart was monitored during the entire experiment by electrocardiography. The frequency components of the arterial diameter, blood pressure, and heart rate were obtained using spectral analysis. Under resting conditions, the radial arterial diameter exhibited a spontaneous oscillation with a period ranging from 45 to 70 s and an amplitude of 80 +/- 14 microns (+/- SE). No very low-frequency mode (< or = 0.02 Hz) was identified in either heart rate or blood pressure. These diameter oscillations affected the distensibility-pressure curves acquired simultaneously. Thus the 3-4% oscillatory variation in arterial diameter was paralleled by a 1.5- to 2-fold change in distensibility. These low-frequency oscillations of large arteries seem to be mediated by an intrinsic vascular mechanism.
在本研究中，我们调查了桡动脉是否存在周期性收缩活动，并评估了这种振荡行为对这条中等大小肌性血管力学特性的影响。使用高精度超声回声跟踪装置，对6名年龄在18 - 42岁的健康男性志愿者的右侧桡动脉内径进行无创测量。同时通过光电容积描记法在同一侧的中指记录血压。在整个实验过程中通过心电图监测心脏的电活动。使用频谱分析获得动脉直径、血压和心率的频率成分。在静息状态下，桡动脉直径呈现出自发振荡，周期为45至70秒，振幅为80±14微米（±标准误）。在心率或血压中均未发现极低频率模式（≤0.02赫兹）。这些直径振荡影响了同时获取的扩张性 - 压力曲线。因此，动脉直径3 - 4%的振荡变化伴随着扩张性1.5至2倍的变化。大动脉的这些低频振荡似乎由一种内在的血管机制介导。
