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食管裂孔疝在延缓胃酸清除中的作用。

Role of hiatal hernia in delaying acid clearance.

作者信息

Stewart R J, Johnston B T, Boston V E, Dodge J

机构信息

Royal Belfast Hospital for Sick Children, Department of Paediatric Surgery.

出版信息

Arch Dis Child. 1993 May;68(5):662-4. doi: 10.1136/adc.68.5.662.

Abstract

The aim of this study was to assess prospectively the relationship of a hiatal hernia to gastro-oesophageal reflux. Ninety five children with symptoms of gastro-oesophageal reflux in whom reflux was demonstrated radiologically were investigated. Oesophageal pH monitoring for 18 hours and endoscopy were performed in all patients. On the basis of radiology, patients were divided into those with hiatal hernia (n = 37) and those without (n = 58). Both groups had the same number of reflux episodes on pH monitoring. However, the median duration of the longest episode was significantly greater in the hiatal hernia group (30 min v 19 min), as was the number of reflux episodes longer than five minutes (5 v 4). The percentage with a pH < 4 just failed to be significantly different (13% v 8%). Hiatal hernia was also found to correlate with the presence of oesophagitis. The presence of a hiatal hernia delays the clearance of acid from the oesophagus and is associated with an increased incidence of oesophagitis.

摘要

本研究的目的是前瞻性评估食管裂孔疝与胃食管反流之间的关系。对95例有胃食管反流症状且经放射学证实存在反流的儿童进行了研究。所有患者均进行了18小时的食管pH监测和内镜检查。根据放射学检查结果,将患者分为食管裂孔疝组(n = 37)和无食管裂孔疝组(n = 58)。两组在pH监测中的反流发作次数相同。然而,食管裂孔疝组最长发作的中位持续时间显著更长(30分钟对19分钟),持续时间超过5分钟的反流发作次数也是如此(5次对4次)。pH值< 4的百分比虽未达到显著差异(13%对8%)。还发现食管裂孔疝与食管炎的存在相关。食管裂孔疝的存在会延迟食管内酸的清除,并与食管炎发病率增加有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e63/1029337/b4217f4e33c6/archdisch00550-0042-a.jpg

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