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小儿食管裂孔疝的20至40年随访

Twenty to 40 year follow up of infantile hiatal hernia.

作者信息

Johnston B T, Carré I J, Thomas P S, Collins B J

机构信息

Department of Medicine, Queen's University of Belfast, Northern Ireland.

出版信息

Gut. 1995 Jun;36(6):809-12. doi: 10.1136/gut.36.6.809.

Abstract

The aim of this study was to assess clinical and radiological findings of gastro-oesophageal reflux in adults who were diagnosed as having a hiatal hernia in infancy or early childhood. One hundred and eighteen patients with a minimum age of 20 who were diagnosed as having a hiatal hernia in childhood were interviewed; barium meal examination was performed in 96 of these cases. Ninety four patients had not required surgery for their hernia. The hiatal hernia persisted in 53% of these patients and 46% experienced heartburn at least monthly but in only three was this severe. Heartburn was significantly more common in patients in whom reflux was seen on barium meal. The consumption of antacids was significantly lower (20% v 46%) in patients who responded well to treatment as children. Eighteen of 24 patients who underwent surgery as children experienced heart-burn monthly but in only one patient was this severe. Two patients underwent endoscopy at their request because of symptoms during this follow up. Both had Barrett's oesophagus. In conclusion, despite the persistence of the hiatal hernia in half of the non-surgically treated patients, few complained of significant symptoms. Effective treatment in childhood was associated with a significant reduction in antacid consumption for heartburn as adults. The finding of Barrett's oesophagus in two patients high-lights a possible role for endoscopic screening in this patient group.

摘要

本研究的目的是评估在婴儿期或幼儿期被诊断为患有食管裂孔疝的成年人胃食管反流的临床和放射学表现。对118名最小年龄为20岁且在儿童期被诊断为患有食管裂孔疝的患者进行了访谈;其中96例患者进行了钡餐检查。94例患者的疝无需手术治疗。这些患者中53%的食管裂孔疝持续存在,46%的患者至少每月出现一次烧心症状,但只有3例症状严重。在钡餐检查中发现有反流的患者烧心症状明显更常见。儿童期对治疗反应良好的患者抗酸剂的使用明显较低(20%对46%)。24名儿童期接受手术的患者中有18名每月出现烧心症状,但只有1例症状严重。在本次随访期间,有2名患者因出现症状应其要求接受了内镜检查。两人均患有巴雷特食管。总之,尽管一半未接受手术治疗的患者食管裂孔疝持续存在,但很少有人抱怨有明显症状。儿童期的有效治疗与成年后烧心时抗酸剂使用的显著减少有关。两名患者中发现巴雷特食管突出了内镜筛查在该患者群体中可能的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a166/1382613/998a483e8005/gut00524-0018-a.jpg

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