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慢性血小板减少症的晚期自发恢复

Late spontaneous recovery of chronic thrombocytopenia.

作者信息

Tait R C, Evans D I

机构信息

Royal Manchester Children's Hospital, Pendlebury.

出版信息

Arch Dis Child. 1993 May;68(5):680-1. doi: 10.1136/adc.68.5.680.

Abstract

Five cases are reported of spontaneous remission of chronic childhood thrombocytopenia four or more years after diagnosis. Other than typical features of chronic idiopathic thrombocytopenic purpura there were no obvious markers predictive of late remission, although a slow progressive recovery was common to four of the patients. In light of this experience splenectomy is not recommended in clinically mild thrombocytopenia.

摘要

报告了5例儿童慢性血小板减少症在诊断后4年或更长时间自发缓解的病例。除了慢性特发性血小板减少性紫癜的典型特征外,没有明显的标志物可预测晚期缓解,尽管4例患者通常有缓慢的渐进性恢复。鉴于这一经验,不建议对临床症状轻微的血小板减少症患者进行脾切除术。

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本文引用的文献

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Management of childhood idiopathic thrombocytopenic purpura.儿童特发性血小板减少性紫癜的管理
Br J Haematol. 1983 May;54(1):11-4. doi: 10.1111/j.1365-2141.1983.tb02062.x.
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Idiopathic thrombocytopenic purpura in childhood.儿童特发性血小板减少性紫癜
J Pediatr. 1966 Jun;68(6):971-9. doi: 10.1016/s0022-3476(66)80218-4.
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Idiopathic thrombocytopenic purpura: an epidemiologic study.
J Pediatr. 1973 Jul;83(1):31-6. doi: 10.1016/s0022-3476(73)80308-7.
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The nontreatment of childhood idiopathic thrombocytopenic purpura.
Eur J Pediatr. 1987 Mar;146(2):107-12. doi: 10.1007/BF02343213.

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