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术后10年或更长时间出现的脾切除术后脓毒症

Postsplenectomy sepsis 10 years or more after operation.

作者信息

Evans D I

出版信息

J Clin Pathol. 1985 Mar;38(3):309-11. doi: 10.1136/jcp.38.3.309.

Abstract

Three new cases (two fatal) of postsplenectomy sepsis occurring 14, 25, and 26 years after operation for hereditary spherocytosis are described. There are now 25 cases in the published work in which this complication occurred 10 or more years after operation, 14 of which were fatal. The mean age of onset is 37 years. The features of the disease are similar to those seen in other postsplenectomy infections, and pneumococcal infection was responsible in 19 cases (76%). The major predisposing illnesses were trauma, hereditary spherocytosis, and idiopathic thrombocytopenia.

摘要

本文描述了3例脾切除术后败血症的新病例(2例死亡),这些病例发生在因遗传性球形红细胞增多症接受手术后14、25和26年。在已发表的文献中,目前有25例该并发症发生在术后10年或更长时间,其中14例死亡。发病的平均年龄为37岁。该疾病的特征与其他脾切除术后感染相似,19例(76%)由肺炎球菌感染引起。主要的易感疾病为创伤、遗传性球形红细胞增多症和特发性血小板减少症。

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本文引用的文献

5
Splenectomy: indications, hazards and alternatives.
Br J Surg. 1984 Mar;71(3):173-80. doi: 10.1002/bjs.1800710302.
6
Fatal post-splenectomy sepsis despite prophylaxis with penicillin and pneumococcal vaccine.
Lancet. 1984 May 19;1(8386):1124. doi: 10.1016/s0140-6736(84)92537-6.
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Hyposplenism and overwhelming pneumococcal infection: a reappraisal.
Am J Med Sci. 1971 Aug;262(2):101-7. doi: 10.1097/00000441-197108000-00005.
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Splenectomy in childhood: a review of 1413 cases.儿童脾切除术:1413例病例回顾
J Pediatr Surg. 1972 Aug-Sep;7(4):382-8. doi: 10.1016/0022-3468(72)90006-1.

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