急性和慢性呼吸窘迫患者拔管方法的随机试验
Randomised trial of methods of extubation in acute and chronic respiratory distress.
作者信息
Chan V, Greenough A
机构信息
Department of Child Health, King's College Hospital, London.
出版信息
Arch Dis Child. 1993 May;68(5 Spec No):570-2. doi: 10.1136/adc.68.5_spec_no.570.
Abstract
Sixty infants (median gestational age 29 weeks) with acute and 60 infants (median gestational age 25 weeks) with chronic respiratory distress were randomised to be extubated either directly into a headbox or onto 3 cm H2O nasal continuous positive airway pressure (CPAP). Our aim was to test the hypothesis that extubation onto nasal CPAP rather than directly into a headbox was more likely to be associated with successful extubation in infants with acute rather than chronic respiratory distress. Overall the failure rate of extubation was approximately 33%, with no significant difference between the infants with acute and chronic respiratory distress. There was no significant difference in the failure rate of extubation among infants randomised to receive nasal CPAP or headbox oxygen in either the acute or chronic respiratory distress groups.
摘要
60例急性呼吸窘迫婴儿（中位胎龄29周）和60例慢性呼吸窘迫婴儿（中位胎龄25周）被随机分为两组，一组直接拔管后置入头罩，另一组拔管后给予3厘米水柱的鼻持续气道正压通气（CPAP）。我们的目的是检验以下假设：对于急性而非慢性呼吸窘迫的婴儿，拔管后给予鼻CPAP而非直接置入头罩更有可能与成功拔管相关。总体而言，拔管失败率约为33%，急性和慢性呼吸窘迫婴儿之间无显著差异。在急性或慢性呼吸窘迫组中，随机接受鼻CPAP或头罩吸氧的婴儿拔管失败率无显著差异。
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