Greenough A, Elias-Jones A, Pool J, Morley C J, Davis J A
Early Hum Dev. 1985 Oct;12(1):15-22. doi: 10.1016/0378-3782(85)90132-x.
40 preterm, ventilated infants (gestational ages 24-33 weeks) were entered into a double-blind randomised trial to assess the effect of oral theophylline on lung function and ventilator dependence. Theophylline administration was associated with a significant improvement in compliance (P less than 0.05) and hastened weaning from ventilation (P less than 0.01).
