拟杆菌属对5-硝基咪唑耐药性的遗传学
Genetics of resistance of Bacteroides species to 5-nitroimidazole.
作者信息
Reysset G, Haggoud A, Sebald M
机构信息
Unité des Anaérobies, Institut Pasteur, Paris, France.
出版信息
Clin Infect Dis. 1993 Jun;16 Suppl 4:S401-3. doi: 10.1093/clinids/16.supplement_4.s401.
Abstract
Thirty-three clinical isolates of Bacteroides strains with a moderate-to-high level of resistance to 5-nitroimidazole were compared with three strains previously studied by Southern blotting of their DNA. Whether plasmid-borne or chromosomally determined, all genetic determinants that are resistant to 5-nitroimidazole belong to two hybridization groups.
摘要
将33株对5-硝基咪唑具有中度至高度抗性的拟杆菌临床分离株与之前通过DNA Southern印迹法研究的3株菌株进行了比较。无论抗性是由质粒介导还是由染色体决定，所有对5-硝基咪唑具有抗性的遗传决定因素都属于两个杂交组。
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