几内亚比绍部分患者样本中结核分枝杆菌的药物敏感性
Drug susceptibility in Mycobacterium tuberculosis of a sample of patients in Guinea Bissau.
作者信息
Dias F, Michael S G, Hoffner S E, Martins L, Norberg R, Källenius G
机构信息
National Bacteriological Laboratory, Stockholm, Sweden.
出版信息
Tuber Lung Dis. 1993 Apr;74(2):129-30. doi: 10.1016/0962-8479(93)90040-5.
Sputum samples from patients with known or suspected tuberculosis were collected in Bissau, Guinea Bissau, and isolates belonging to the Mycobacterium tuberculosis complex (M. tuberculosis, M. bovis or M. africanum) were examined for their susceptibility to the 4 drugs streptomycin, isoniazid, ethambutol and rifampicin. Of 59 M. tuberculosis complex isolates only 2 were resistant to any of the drugs (isoniazid). Thus there is little resistance to these first line drugs among M. tuberculosis isolates from patients in Guinea Bissau.
在几内亚比绍的比绍，收集了已知或疑似结核病患者的痰液样本，并对属于结核分枝杆菌复合群（结核分枝杆菌、牛分枝杆菌或非洲分枝杆菌）的分离株进行了对链霉素、异烟肼、乙胺丁醇和利福平这4种药物的敏感性检测。在59株结核分枝杆菌复合群分离株中，只有2株对任何一种药物（异烟肼）耐药。因此，几内亚比绍患者的结核分枝杆菌分离株对这些一线药物的耐药性很低。
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