Balcazar H
Department of Family Resources and Human Development, Arizona State University, Tempe 85287-2502.
Ethn Dis. 1993 Spring;3(2):169-75.
This study was designed to evaluate the prevalence of intrauterine growth retardation (IUGR) in Mexican Americans compared to non-Hispanic whites in Arizona. Data were compiled from birth certificates documenting live births in 1986 and 1987. A total of 25,289 Mexican-American and 71,139 white newborns were classified by IUGR. Two methods of IUGR classification were used: the fetal growth ratio (FGR) and the 10th percentile of birthweight by gestational age. A reference growth-distribution data set from the state of California was used to determine IUGR vs non-IUGR newborns. Maternal risk factors were also used to compare IUGR and non-IUGR samples. Overall, Mexican Americans had a lower risk (OR: 0.91) for IUGR than did whites, after controlling for maternal risk factors. Regardless of the IUGR classification method used, more than 88% of IUGR infants were born at term, and more than 60% of IUGR infants had birthweights equal to or greater than 2500 g. Maternal risk factors significantly discriminated between IUGR and non-IUGR infants. Finally, after controlling for maternal risk factors, US-born Mexican mothers were 1.21 times more likely to have an IUGR infant than were Mexico-born mothers. The problem of IUGR and its determinants in Mexican Americans deserves attention in clinical settings.
本研究旨在评估与亚利桑那州非西班牙裔白人相比，墨西哥裔美国人中宫内生长迟缓（IUGR）的患病率。数据来自记录1986年和1987年活产情况的出生证明。共有25289名墨西哥裔美国新生儿和71139名白人新生儿按宫内生长迟缓进行了分类。采用了两种宫内生长迟缓分类方法：胎儿生长比（FGR）和按孕周计算的出生体重第10百分位数。使用来自加利福尼亚州的参考生长分布数据集来确定宫内生长迟缓与非宫内生长迟缓新生儿。还使用母亲的风险因素来比较宫内生长迟缓和非宫内生长迟缓样本。总体而言，在控制了母亲的风险因素后，墨西哥裔美国人患宫内生长迟缓的风险（比值比：0.91）低于白人。无论采用何种宫内生长迟缓分类方法，超过88%的宫内生长迟缓婴儿为足月儿，超过60%的宫内生长迟缓婴儿出生体重等于或大于2500克。母亲的风险因素在宫内生长迟缓和非宫内生长迟缓婴儿之间有显著差异。最后，在控制了母亲的风险因素后，在美国出生的墨西哥母亲生出宫内生长迟缓婴儿的可能性是在墨西哥出生的母亲的1.21倍。墨西哥裔美国人中宫内生长迟缓及其决定因素的问题在临床环境中值得关注。
