实验性海洛因所致肌病：超微结构观察
Experimental heroin-induced myopathy: ultrastructural observations.
作者信息
Peña J, Luque E, Aranda C, Jimena I, Vaamonde R
机构信息
Department of Morphological Sciences (Histology), Faculty of Medicine, University of Córdoba, Spain.
出版信息
J Submicrosc Cytol Pathol. 1993 Apr;25(2):279-84.
PMID:8324730
Abstract
Electron microscopic analysis was used to study the ultrastructural changes taking place in rat soleus muscle following intraperitoneal administration of pure heroin. Degenerative changes observed consisted primarily of hypercontracted fibers at different stages of development. Evidence of regeneration was also found. Results show the myotoxic effect of pure heroin on skeletal muscle. The pathogenesis of muscle damage is discussed.
摘要
采用电子显微镜分析技术研究了腹腔注射纯海洛因后大鼠比目鱼肌发生的超微结构变化。观察到的退行性变化主要包括处于不同发育阶段的过度收缩纤维。还发现了再生的证据。结果显示了纯海洛因对骨骼肌的肌毒性作用。并对肌肉损伤的发病机制进行了讨论。
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Experimental heroin-induced myopathy: ultrastructural observations.实验性海洛因所致肌病：超微结构观察
J Submicrosc Cytol Pathol. 1993 Apr;25(2):279-84.
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