Diaz P T, Clanton T L
Department of Internal Medicine, Ohio State University, Columbus.
Chest. 1993 Jul;104(1):313-5. doi: 10.1378/chest.104.1.313.
Recent reports have suggested an association between primary pulmonary hypertension and human immunodeficiency virus (HIV) infection. This appears to be an accelerated syndrome, associated with a relatively brief duration of symptoms, yet prominent right ventricular failure and severe pulmonary hypertension on presentation. We present a case of a primary pulmonary hypertension in a 35-year-old HIV-seropositive hemophiliac. His accelerated clinical course is consistent with previously reported cases of HIV-related pulmonary hypertension. However, this patient's pulmonary function tests revealed marked hyperinflation, a decreased diffusing capacity, and no airflow obstruction. To our knowledge, this very usual constellation of pulmonary function changes has not been described previously in this syndrome.
最近的报告表明，原发性肺动脉高压与人类免疫缺陷病毒（HIV）感染之间存在关联。这似乎是一种进展加速的综合征，症状持续时间相对较短，但就诊时右心室衰竭和严重肺动脉高压较为突出。我们报告一例35岁HIV血清学阳性血友病患者的原发性肺动脉高压病例。他进展加速的临床病程与先前报道的HIV相关肺动脉高压病例一致。然而，该患者的肺功能测试显示有明显的肺过度充气、弥散功能降低且无气流阻塞。据我们所知，这种非常不常见的肺功能变化组合在该综合征中此前尚未被描述过。
