Jacques C, Richmond G, Tierney L, Curtis J L, McKerrow J, Warnock M L
Anatomic Pathology Service, Department of Veterans Affairs Medical Center, San Francisco, CA.
Hum Pathol. 1992 Feb;23(2):191-4. doi: 10.1016/0046-8177(92)90243-v.
We describe clinical and postmortem findings in a 44-year-old man with pulmonary hypertension and infection with the human immunodeficiency virus (HIV-1). Plexogenic angiopathy and veno-occlusive lesions were present, in addition to a mild, patchy pulmonary interstitial lymphoid infiltrate. The clinical data for 14 previously reported cases of HIV-associated primary pulmonary hypertension are summarized. We speculate that these vascular changes may be due to damage from a specific immune response to HIV.
我们描述了一名44岁患有肺动脉高压且感染人类免疫缺陷病毒（HIV-1）的男性患者的临床和尸检结果。除了轻度的、斑片状肺间质淋巴浸润外，还存在丛状血管病和静脉闭塞性病变。总结了14例先前报道的HIV相关原发性肺动脉高压病例的临床资料。我们推测这些血管变化可能是由于对HIV的特异性免疫反应造成的损害所致。
