粪生粪壳菌b2位点的基因内抑制。I. 三种不同抑制类型的鉴定。
Intragenic suppression at the b2 locus in Ascobolus immersus. I. Identification of three distinct groups of suppression.
作者信息
Leblon G, Paquette N
出版信息
Genetics. 1978 Nov;90(3):475-88. doi: 10.1093/genetics/90.3.475.
Abstract
A reversion study of EMS- or ICR170-induced ascospore color mutants in Ascobolus immersus is reported. Twenty-three new intragenic suppressors were isolated within the b2 locus. These are localized within three distinct groups on a genetic fine-structure map containing 21 identifiable sites. The pattern of reversion is discussed according to the known specificity of EMS and ICR170 in Ascobolus immersus.
摘要
本文报道了对浸没盘菌中EMS或ICR170诱导的子囊孢子颜色突变体的回复突变研究。在b2基因座内分离出23个新的基因内抑制子。它们定位在一个包含21个可识别位点的遗传精细结构图谱的三个不同组内。根据EMS和ICR170在浸没盘菌中的已知特异性，讨论了回复突变的模式。
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Intragenic suppression at the b2 locus in Ascobolus immersus. I. Identification of three distinct groups of suppression.粪生粪壳菌b2位点的基因内抑制。I. 三种不同抑制类型的鉴定。
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本文引用的文献
1
A genetic and biochemical analysis of second site reversion.二次位点回复突变的遗传与生化分析。
J Biol Chem. 1963 Mar;238:1043-8.
2
General nature of the genetic code for proteins.蛋白质遗传密码的一般性质。
Nature. 1961 Dec 30;192:1227-32. doi: 10.1038/1921227a0.
3
Base composition of nonsense codons in E. coli. Evidence from amino-acid substitutions at a tryptophan site in alkaline phosphatase.大肠杆菌中无义密码子的碱基组成。来自碱性磷酸酶色氨酸位点氨基酸取代的证据。
Nature. 1965 Jun 5;206(988):992-4. doi: 10.1038/206992a0.
4
Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday.移码突变与遗传密码。本文谨献给西奥多修斯·杜布赞斯基教授，以庆祝他66岁生日。
Cold Spring Harb Symp Quant Biol. 1966;31:77-84. doi: 10.1101/sqb.1966.031.01.014.
5
Nonsense codons.无义密码子。
Cold Spring Harb Symp Quant Biol. 1966;31:173-9. doi: 10.1101/sqb.1966.031.01.025.
6
External suppression of a frameshift mutant in salmonella.沙门氏菌中移码突变体的外部抑制
J Mol Biol. 1968 Jun 28;34(3):541-57. doi: 10.1016/0022-2836(68)90179-4.
7
Altered amino acid sequences produced by reversion of frameshift mutants of tryptophan synthetase A gene of E. coli.大肠杆菌色氨酸合成酶A基因移码突变体回复产生的氨基酸序列改变。
Proc Natl Acad Sci U S A. 1967 Oct;58(4):1499-506. doi: 10.1073/pnas.58.4.1499.
8
Amino acid replacements and the genetic code.氨基酸替换与遗传密码
Cold Spring Harb Symp Quant Biol. 1966;31:151-62. doi: 10.1101/sqb.1966.031.01.023.
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