Akabani G
Battelle Pacific Northwest Laboratory, Health Physics Dept., Richland, WA 99352.
J Nucl Med. 1993 Aug;34(8):1361-6.
A mathematical model of a Haversian canal was used to calculate absorbed dose factors for 90Sr, 90Y, 45Ca, 89Sr, 32P, 131I and 153Sm. The regions of interest considered in this study were the blood canal, the wall or bone surface and the bone matrix. The source regions were the blood canal and the bone surface. Absorbed dose calculations were performed with the EGS4-PRESTA Monte Carlo transport code. Dose factors were calculated for Haversian canals of 5-microns to 50-microns radius. These data are also tabulated so that dose factors can be evaluated for other radii. An example is given in which these data are used along with a biokinetic model of a radioactive material in bone to assess doses from diagnostic and radiotherapy procedures.
利用哈弗斯管的数学模型来计算90Sr、90Y、45Ca、89Sr、32P、131I和153Sm的吸收剂量因子。本研究中考虑的感兴趣区域为血管、骨壁或骨表面以及骨基质。源区域为血管和骨表面。使用EGS4-PRESTA蒙特卡罗传输代码进行吸收剂量计算。针对半径为5微米至50微米的哈弗斯管计算剂量因子。这些数据也制成了表格，以便能评估其他半径的剂量因子。给出了一个示例，其中这些数据与骨中放射性物质的生物动力学模型一起用于评估诊断和放射治疗程序的剂量。
