Atala A, Kavoussi L R, Goldstein D S, Retik A B, Peters C A
Pediatric Urology Research Laboratory, Children's Hospital, Boston, Massachusetts.
J Urol. 1993 Aug;150(2 Pt 2):748-51. doi: 10.1016/s0022-5347(17)35604-5.
Major advances have been made in the area of laparoscopic surgery. The advantages of this approach include smaller incisions, shorter hospitalizations, a more rapid convalescence and decreased postoperative discomfort. To explore the technical feasibility of performing antireflux surgery laparoscopically, we conducted a pilot study in 4 mini-pigs in which bilateral vesicoureteral reflux had been created surgically. We applied a modification of the Lich extravesical ureteral approach to perform laparoscopic antireflux surgery. All mini-pigs underwent successful unilateral mobilization, creation of a bladder wall trough and creation of a new ureteral tunnel laparoscopically. Examinations were performed postoperatively, and then serially at 1, 2, 3 and 5 months after repair. Fluoroscopic cystograms demonstrated the resolution of reflux in the corrected ureters and persistence of reflux in the uncorrected control ureters in all animals. Excretory urography showed no evidence of obstruction. Laparoscopic correction of vesicoureteral reflux appears to be technically feasible in the animal model. Long-term followup is necessary to determine the possible applicability of this technique in humans.
腹腔镜手术领域已取得重大进展。这种手术方式的优点包括切口更小、住院时间更短、康复更快以及术后不适减轻。为探讨腹腔镜下抗反流手术的技术可行性,我们对4只经手术制造双侧膀胱输尿管反流的小型猪进行了一项初步研究。我们采用改良的利奇膀胱外输尿管术式来实施腹腔镜抗反流手术。所有小型猪均成功地在腹腔镜下进行了单侧输尿管游离、膀胱壁槽的创建以及新输尿管隧道的构建。术后进行了检查,然后在修复后的1、2、3和5个月进行了系列检查。荧光透视膀胱造影显示,所有动物中,矫正后的输尿管反流消失,未矫正的对照输尿管反流持续存在。排泄性尿路造影未显示梗阻迹象。在动物模型中,腹腔镜矫正膀胱输尿管反流在技术上似乎是可行的。需要进行长期随访以确定该技术在人类中的可能适用性。