Mandell J, Peters C A, Estroff J A, Allred E N, Benacerraf B R
Department of Surgery, Children's Hospital, Boston, Massachusetts.
J Urol. 1993 Aug;150(2 Pt 2):790-2. doi: 10.1016/s0022-5347(17)35614-8.
The occurrence of prenatal compensatory renal growth has remained in question, despite the general acceptance of this phenomenon postnatally. We measured by ultrasound imaging the renal length of 22 human fetuses with a solitary kidney or contralateral multicystic dysplastic kidney, and compared it to measurements in 40 normal control fetuses. Renal length was normalized to fetal biparietal diameter. Analysis of covariance showed that the solitary kidneys were significantly larger than normal controls (p < 0.0001), although the rate of growth was not significantly increased above normal. These data document the presence of compensatory renal growth in human fetuses with solitary or functionally solitary kidneys.
尽管产后代偿性肾生长现象已被广泛接受，但产前是否会出现这种现象仍存在疑问。我们通过超声成像测量了22例单肾或对侧多囊性发育不良肾的人类胎儿的肾长度，并将其与40例正常对照胎儿的测量结果进行比较。肾长度以胎儿双顶径进行标准化。协方差分析显示，单肾明显大于正常对照组（p < 0.0001），尽管生长速率并未显著高于正常水平。这些数据证明了患有单肾或功能上相当于单肾的人类胎儿存在代偿性肾生长。
