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[视交叉放线菌性肉芽肿:一例报告]

[Actinomycotic granuloma of the optic chiasma: a case report].

作者信息

Toyoda O, Nojiri K, Nakajima H

机构信息

Department of Neurosurgery, Central Gunma Neurosurgical Hospital, Japan.

出版信息

No Shinkei Geka. 1993 Jul;21(7):623-7.

PMID:8327054
Abstract

A case of actinomycotic granuloma of the optic chiasma and the optic nerve is reported. A 53-year-old man was admitted to our hospital with headache and vomiting on September 25, 1989. General physical and neurological examination on admission revealed no remarkable findings. CT-scan demonstrated almost normal pictures. On the 17th hospital day, his temperature was 38 degrees C and white blood cell (WBC) count was 12000 cumm. And he presented right abducens palsy. MRI demonstrated no abnormal findings then. After antibiotic therapy of penicillin intravenously for 4 days, his temperature returned to normal and abducens palsy disappeared for two weeks. He was discharged 43 days after admission. But one year after discharge he developed progressive impairment of right visual acuity. He was admitted to our hospital again on January 19, 1991. His neurological examination revealed severe impairment of right visual acuity and bitemporal hemianopsia. WBC count was 5400 and CRP was negative and temperature was 36.2 degrees C. CT-scan and MRI demonstrated a suprasellar enhancing mass lesion. Serum prolactin was 38 ng/ml. A diagnosis of pituitary adenoma was considered and a right frontotemporal craniotomy was performed. At operation, abnormally swelled right optic nerve and chiasma were found and the swelled chiasma only was resected. Histological examination showed an abscess containing necrotic tissues and actinomycotic granules with radiating filaments. The patient was given penicillin intravenously for 37 days and orally for two months. At that time, MRI revealed no abnormal enhancing lesion, and his visual acuity improved gradually. Actinomycosis of the optic nerve and chiasma is very rare.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

报告了一例视交叉和视神经放线菌性肉芽肿病例。一名53岁男性于1989年9月25日因头痛和呕吐入院。入院时全身体格检查和神经检查均未发现明显异常。CT扫描显示图像基本正常。住院第17天,他体温38摄氏度,白细胞计数为12000/立方毫米。并且出现了右侧展神经麻痹。当时MRI未显示异常。静脉注射青霉素抗生素治疗4天后,他的体温恢复正常,展神经麻痹消失了两周。入院43天后出院。但出院一年后,他出现了右眼视力进行性损害。1991年1月19日他再次入院。神经检查显示右眼视力严重损害和双颞侧偏盲。白细胞计数为5400,C反应蛋白为阴性,体温为36.2摄氏度。CT扫描和MRI显示鞍上有强化的肿块病变。血清催乳素为38纳克/毫升。考虑诊断为垂体腺瘤,并进行了右额颞开颅手术。手术中,发现右侧视神经和视交叉异常肿胀,仅切除了肿胀的视交叉。组织学检查显示一个含有坏死组织和放线菌颗粒及放射状细丝的脓肿。给患者静脉注射青霉素37天,口服两个月。当时,MRI显示没有异常强化病变,他的视力逐渐改善。视神经和视交叉放线菌病非常罕见。(摘要截短至250字)

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