Raynaud E, Audran M, Pages J C, Brun J F, Fedou C, Chanal J L, Orsetti A
Service d'Exploration Physiologique des Hormones et des Métabolismes, Hôpital Lapeyronie, Montpellier, France.
Pathol Biol (Paris). 1993 Feb;41(2):159-63.
Urinary testosterone to epitestosterone ratio (T/E) is used as a marker for illegal exogenous testosterone use. Mean value in healthy adults is 1.13 and 6 is the upper limit of the accepted range. Urinary excretion of these two steroids were studied in 57 children and teenagers at different pubertal stages, using gas chromatography coupled with mass spectrometry with selective ion detection. Urinary excretion of testosterone and epitestosterone increased significantly during puberty. Mean T/E ratio remained fairly constant but interindividual variations were marked and in one subject the T/E ratio exceeded 6. These data suggest that this test may yield false-positive results in adolescents.
尿睾酮与表睾酮比值（T/E）被用作非法使用外源性睾酮的标志物。健康成年人的平均值为1.13，公认范围的上限为6。采用气相色谱-质谱联用选择性离子检测法，对57名处于不同青春期阶段的儿童和青少年的这两种类固醇的尿排泄情况进行了研究。青春期期间，睾酮和表睾酮的尿排泄量显著增加。平均T/E比值保持相当稳定，但个体间差异明显，有一名受试者的T/E比值超过了6。这些数据表明，该检测在青少年中可能会产生假阳性结果。
