Evfim'evskiĭ V P, Adamovich N V, Sokolova T P, Grinenko N V
Probl Tuberk. 1993(1):14-8.
The results of the clinico-roentgenologic and functional examination of 434 patients with different forms of pulmonary tuberculosis were subjected to analysis. The obstructive syndrome of ventilation disorders was detected in more than 60% of pulmonary tuberculosis patients. The prevalent significance in its pathogenesis was played by disorders of patency of fine bronchi and air distribution in the lungs. They were associated with extension and activity of the processes and their tendency to acquire a chronic form and with the action of nonspecific factors on the bronchi, which included smoking, work under dust-contaminated conditions, concurrent nonspecific pulmonary diseases, nonspecific changes of the principal bronchi revealed by bronchoscopy and structural nonspecific changes of the peripheral air ways detected by a morphologic study of the resected material. A bronchospastic component was responsible for the broncho-obstructive syndrome in 57% of the patients.
对434例不同类型肺结核患者的临床-放射学及功能检查结果进行了分析。60%以上的肺结核患者存在通气障碍的阻塞综合征。细支气管通畅性障碍及肺部气体分布异常在其发病机制中起主要作用。它们与病变的扩展、活动度及其慢性化倾向有关，也与非特异性因素对支气管的作用有关，这些因素包括吸烟、在粉尘污染环境中工作、并发非特异性肺部疾病、支气管镜检查发现的主支气管非特异性改变以及对切除标本进行形态学研究发现的外周气道结构非特异性改变。57%的患者支气管阻塞综合征由支气管痉挛因素所致。
