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[结核病患者血液单核细胞杀菌能力的评估]

[An assessment of the bactericidal capacity of the blood monocytes in tuberculosis patients].

作者信息

Mel'nikov V P

出版信息

Probl Tuberk. 1993(1):45-7.

PMID:8327440
Abstract

The nitro-blue tetrasolum (NBT) test was used for the study of the bactericidal capacity of blood monocytes in 30 healthy subjects and 86 pulmonary tuberculosis patients. The monocyte capacity of tuberculosis patients to restore NBT in the process of phagocytosis was found to be reduced. The NPT test parameters in the absence of cell stimulation were the same in both groups of the examined subjects. Administration of 50 TU of tuberculin subcutaneously is accompanied by the lowered capacity of monocytes to restore NPT during phagocytosis in patients with minimal activity of the tuberculous process, while this capacity was increased in subjects with post-tuberculous changes in the lungs.

摘要

采用硝基蓝四氮唑(NBT)试验研究了30名健康受试者和86例肺结核患者血液单核细胞的杀菌能力。发现肺结核患者单核细胞在吞噬过程中还原NBT的能力降低。在未进行细胞刺激的情况下,两组受检者的NPT试验参数相同。皮下注射50 TU结核菌素后,结核病变活动度极小的患者单核细胞在吞噬过程中还原NPT的能力降低,而肺部有结核后改变的受试者这一能力增强。

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