头孢菌素酶在铜绿假单胞菌临床分离株碳青霉烯类耐药中的作用。
Role of cephalosporinase in carbapenem resistance of clinical isolates of Pseudomonas aeruginosa.
作者信息
Zhou X Y, Kitzis M D, Gutmann L
机构信息
Laboratoire de Microbiologie Médicale, Université Paris VI, France.
出版信息
Antimicrob Agents Chemother. 1993 Jun;37(6):1387-9. doi: 10.1128/AAC.37.6.1387.
Abstract
With numerous imipenem-resistant clinical isolates of Pseudomonas aeruginosa as well as in vitro-selected resistant mutants, we have demonstrated, by a simple method with a powerful cephalosporinase inhibitor, BRL42715, the contribution of chromosomal cephalosporinase in resistance to imipenem in this species.
摘要
利用众多耐亚胺培南的铜绿假单胞菌临床分离株以及体外筛选的耐药突变体，我们通过一种使用强效头孢菌素酶抑制剂BRL42715的简单方法，证明了染色体头孢菌素酶在该菌对亚胺培南耐药性中的作用。
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