Grillo H C, Mark E J, Mathisen D J, Wain J C
General Thoracic Surgical Unit, Massachusetts General Hospital, Boston 02114.
Ann Thorac Surg. 1993 Jul;56(1):80-7. doi: 10.1016/0003-4975(93)90406-8.
We describe idiopathic laryngotracheal and upper tracheal stenosis in 49 patients with no other cause for their stenosis. Traumatic, iatrogenic, infectious, and specific inflammatory processes were excluded. Histopathologically dense fibrosis of keloidal type thickened the lamina propria and choked the ducts of mucous glands but did not destroy cartilage. Thirty-five patients were treated by single-stage resection and reconstruction: 29 by laryngotracheal resection with laryngotracheoplasty and 6 by cricotracheal segmental resection. Thirty-two patients achieved good or excellent results in respiration and voice, 2 needed annual dilations, and 1 required permanent tracheostomy.
我们描述了49例无其他狭窄病因的特发性喉气管及上段气管狭窄患者。排除了创伤性、医源性、感染性及特异性炎症过程。组织病理学显示，瘢痕疙瘩型致密纤维化使固有层增厚，堵塞黏液腺导管，但未破坏软骨。35例患者接受了一期切除重建治疗：29例行喉气管切除并喉气管成形术，6例行环状气管节段切除。32例患者在呼吸和嗓音方面取得了良好或极佳的效果，2例需要每年进行扩张，1例需要永久性气管造口术。
