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两岁以内儿童的脑肿瘤:40例病例回顾

Brain tumors in the first two years of life: a review of forty cases.

作者信息

Reed U C, Rosemberg S, Gherpelli J L, Matushita H, de Almeida G G, Diament A J

机构信息

Department of Neurology, University of São Paulo School of Medicine, Brazil.

出版信息

Pediatr Neurosurg. 1993 Jul-Aug;19(4):180-5. doi: 10.1159/000120728.

DOI:10.1159/000120728
PMID:8329302
Abstract

From 1962 to 1989, 40 infants with brain tumors and less than 2 years old were treated at the Department of Neurology of the Clinical Hospital of the University of São Paulo Medical School. The clinical and neuropathological findings were reviewed as to histological diagnosis, age, sex, signs and symptoms, therapy and outcome. Medulloblastoma was the most common histological type (n = 11), followed by ependymoma (n = 9), choroid plexus tumor (n = 6), astrocytoma (n = 3) and primitive neuroectodermal tumor (n = 2). The tumor was infratentorial in 21 infants, supratentorial in 18 and disseminated in 1.

摘要

1962年至1989年期间,圣保罗大学医学院临床医院神经科对40名年龄小于2岁的脑肿瘤婴儿进行了治疗。对其临床和神经病理学检查结果进行了回顾,内容包括组织学诊断、年龄、性别、体征和症状、治疗方法及治疗结果。髓母细胞瘤是最常见的组织学类型(n = 11),其次是室管膜瘤(n = 9)、脉络丛肿瘤(n = 6)、星形细胞瘤(n = 3)和原始神经外胚层肿瘤(n = 2)。21名婴儿的肿瘤位于幕下,18名位于幕上,1名呈播散性。

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Brain tumors in the first two years of life: a review of forty cases.两岁以内儿童的脑肿瘤:40例病例回顾
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High-grade glioma in very young children: a rare and particular patient population.极低龄儿童的高级别胶质瘤:一个罕见且特殊的患者群体。
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Supratentorial cystic hemangioblastoma with infratentorial extension--a unique location and a rare infant case.
伴有幕下延伸的幕上囊性血管母细胞瘤——独特的位置及罕见的婴儿病例
Childs Nerv Syst. 2006 Sep;22(9):1177-81. doi: 10.1007/s00381-006-0052-4. Epub 2006 Mar 14.
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The role of surgery in pediatric gliomas.手术在儿童胶质瘤中的作用。
J Neurooncol. 1999 May;42(3):271-88. doi: 10.1023/a:1006107227856.
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Will high dose chemotherapy followed by autologous bone marrow transplantation supplant cranio-spinal irradiation in young children treated for medulloblastoma?对于接受髓母细胞瘤治疗的幼儿,高剂量化疗后进行自体骨髓移植会取代颅脊髓照射吗?
J Neurooncol. 1996 Jan;27(1):87-98. doi: 10.1007/BF00146088.