Hazmiri Fatima-Ezzahra, Boukis Fatima, Benali Said Ait, Ganouni Najat Cherif Idrissi El, Rais Hanane
Service d'Anatomie Pathologique, CHU Mohammed VI, Hôpital Arrazi, Marrakech, Maroc.
Service de Neurochirurgie, CHU Mohammed VI, Hôpital Arrazi, Marrakech, Maroc.
Pan Afr Med J. 2018 Aug 24;30:291. doi: 10.11604/pamj.2018.30.291.13208. eCollection 2018.
Brain tumors are the most diagnosed solid tumors in children under the age of 15 years worldwide. However, the epidemiological and anatomopathological profile of these tumors has been poorly described in African and, particularly, in Moroccan literature. This study highlights the epidemiological and anatomopathological peculiarities of primary brain tumors in children living in the region of Marrakech (south Morocco). We conducted a retrospective study in the Division of Anatomic Pathology at the Mohammed VI University Hospital, Marrakech from 2004 to 2016. One hundred and thirty-six patients were diagnosed with primary brain tumor, a mean of 11.33 cases per year. The average age of patients was 8.28 years. Sex-ratio (M/F) was 1.6 with a slight male predominance. Infratentorial tumors were found in 61,53% of cases while supratentorial tumors were found in 38.47% of cases. Infratentorial tumors mainly occurred in the cerebellar hemisphere (61.4%). Eighteen histological types were diagnosed. Astrocytoma and medulloblastoma accounted for 46,32% (29.41% and 16.91%, respectively). In our context, the majority of brain tumors in children was predominant in both age groups: 5-9 years and 10-15 years. The epidemiological data of these tumors from south Morocco are mostly consistent with those already published in North Country's literature and in other non-african countries' literature.
脑肿瘤是全球15岁以下儿童中诊断最多的实体瘤。然而，非洲尤其是摩洛哥文献中对这些肿瘤的流行病学和解剖病理学特征描述甚少。本研究强调了居住在马拉喀什地区（摩洛哥南部）儿童原发性脑肿瘤的流行病学和解剖病理学特点。我们于2004年至2016年在马拉喀什穆罕默德六世大学医院解剖病理科进行了一项回顾性研究。136例患者被诊断为原发性脑肿瘤，平均每年11.33例。患者的平均年龄为8.28岁。性别比（男/女）为1.6，男性略占优势。幕下肿瘤占61.53%，幕上肿瘤占38.47%。幕下肿瘤主要发生在小脑半球（61.4%）。诊断出18种组织学类型。星形细胞瘤和髓母细胞瘤占46.32%（分别为29.41%和16.91%）。在我们的研究背景下，儿童脑肿瘤在两个年龄组中占大多数：5 - 9岁和10 - 15岁。来自摩洛哥南部这些肿瘤的流行病学数据大多与北方国家文献以及其他非非洲国家文献中已发表的数据一致。
