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筛查发现的腹主动脉瘤的自然病史。

Natural history of abdominal aortic aneurysm detected by screening.

作者信息

Bengtsson H, Nilsson P, Bergqvist D

机构信息

Department of Surgery, Lund University, Malmö General Hospital, Sweden.

出版信息

Br J Surg. 1993 Jun;80(6):718-20. doi: 10.1002/bjs.1800800613.

DOI:10.1002/bjs.1800800613
PMID:8330153
Abstract

A group of 88 patients with abdominal aortic dilation found in four ultrasonographic screening studies was followed prospectively by repeated ultrasonography. The initial aortic diameter ranged between 18 and 70 mm. In 19 patients (22 per cent) the aortic diameter exceeded 39 mm. The mean (s.e.m.) annual expansion rate of dilatations < 40 mm in diameter was 0.8 (1.2) mm; among those > or = 40 mm it was 3.3 (1.2) mm. The expansion rate increased with increasing initial diameter. Thirty-eight patients died; the overall mortality rate in the group was high in comparison with an age- and sex-matched population. One patient died after elective aneurysm surgery but none died from a ruptured aneurysm. In conclusion, in about 80 per cent of dilatations found in screening studies the aortic diameter was < 40 mm, with a low risk of rupture. One annual rescanning of an aneurysm < 35 mm in diameter is sufficient; a high overall mortality rate must be expected.

摘要

在四项超声筛查研究中发现的88例腹主动脉扩张患者,通过重复超声检查进行前瞻性随访。初始主动脉直径在18至70毫米之间。19例患者(22%)的主动脉直径超过39毫米。直径<40毫米的扩张的平均(标准误)年扩张率为0.8(1.2)毫米;在直径>或=40毫米的患者中,年扩张率为3.3(1.2)毫米。扩张率随初始直径的增加而增加。38例患者死亡;与年龄和性别匹配的人群相比,该组的总体死亡率较高。1例患者在择期动脉瘤手术后死亡,但无1例死于动脉瘤破裂。总之,在筛查研究中发现的约80%的扩张中,主动脉直径<40毫米,破裂风险较低。直径<35毫米的动脉瘤每年进行一次重新扫描就足够了;必须预期总体死亡率较高。

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引用本文的文献

1
Improved assessment and treatment of abdominal aortic aneurysms: the use of 3D reconstructions as a surgical guidance tool in endovascular repair.改善腹主动脉瘤的评估和治疗:三维重建在血管内修复中的应用作为手术指导工具。
Ir J Med Sci. 2009 Sep;178(3):321-8. doi: 10.1007/s11845-009-0318-4. Epub 2009 Mar 25.
2
Ultrasonography performed by primary care residents for abdominal aortic aneurysm screening.基层医疗住院医师进行的腹部主动脉瘤筛查超声检查。
J Gen Intern Med. 2001 Dec;16(12):845-9. doi: 10.1111/j.1525-1497.2001.01128.x.
3
The case against a national screening programme for aortic aneurysms.
反对全国性主动脉瘤筛查计划的理由。
Ann R Coll Surg Engl. 1997 Mar;79(2):90-5.