Vanni R, Dal Cin P, Marras S, Moerman P, Andria M, Valdes E, Deprest J, Van den Berghe H
Istituto di Biologia Generale, University of Cagliari, Italy.
Cancer Genet Cytogenet. 1993 Jul 1;68(1):32-3. doi: 10.1016/0165-4608(93)90070-3.
Clustering of aberrations to specific chromosome regions of benign tumors may indicate the location of genes related to the proliferative process. Although few endometrial polyps have been cytogenetically investigated, 6p21 band appears to be involved consistently in the chromosome changes. We report two cases of this type of benign tumor with chromosome rearrangements in 12q14-15, allowing identification of a second cytogenetic subgroup in endometrial polyps.
良性肿瘤的畸变聚集于特定染色体区域可能表明与增殖过程相关基因的位置。尽管很少有子宫内膜息肉进行过细胞遗传学研究，但6p21带似乎始终参与染色体变化。我们报告了两例这种类型的良性肿瘤，其12q14 - 15存在染色体重排，从而确定了子宫内膜息肉的第二个细胞遗传学亚组。
